MODIFICATION OF ION MOBILITY SEPARATION USING VOLATILE ORGANIC DOPANTS ON A QUADRUPOLE-ION MOBILITY-ORTHOGONAL TIME-OF-FLIGHT MASS SPECTROMETER.

摘要

Ion-Molecule interactions with polar solvents result in compound specific changes in IMS drift time. Different electronic states of the same ion may be separated due to differences in solvation. For carbofuran, multiple sites of protonation may account for differences in solvation. Study of the effect of dopants on IMS drift time has potential to yield information on: Ion-molecule binding energies. Electronic and stereo chemical information. Solvation effects in biological systems.