SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF NATURAL ANTIMICROBIAL PEPTIDES AND CONVENTIONAL ANTIBIOTICS

摘要

The purpose of this study was to investigate the in vitro activity of natural antimicrobial peptides: citropin 1.1 (GLFDVIKKVASVIGGL-NH2), piscidin 1 (FFHHIFRGIVHVGKTIHRLVTG-NH2), protegrin 1 (RGGRLCYCRRRFCV-CVGR-NH2), temporin A (FLPLIGRVLSGIL-NH2), uperin 3.6 (GVIDAAKKV-VNVLKNLF-NH2) and three chemically engineered analogues of antimicrobial peptides: iseganan IB-367 (RGGLCYCRGRFCVCVGR-NH2), omiganan MSI-226 (ILRWPWWPWRRK-NH2) and pexiganan MBI-78 (GIGKFLKKAKKFG-KAFVKILKK-NH2).