Bile acids and liver fibrosis -causative agent and therapeutic tool

摘要

Depending on the cause of liver injury hepatic fibrosis can present as biliary-type fibrosis with portal-portal septa (e.g. cholangiopathies), bridging fibrosis including portal-central septa (e.g. viral and autoimmune hepatitis), pericellular/sinusoidal fibrosis (e.g. ASH/NASH), and centrolobular fibrosis (e.g. venous-outflow obstruction). This chapter focuses on the pathogenesis of biliary-type fibrosis.