HIGH-PRESSURE PHOTOIONIZATION TIME OF ?IGHT MASS SPECTROMETRY COMBINED WITH DYNAMIC PURGE-INJECTION FOR RAPID ANALYSIS OF VOLATILE METABOLITES IN URINE

摘要

Small molecule metabolites are widely used as biomarkers in the research ?eld of metabolomics for disease diagnosis and exposure assessment. As a readily available biofluid containing plenty of volatile organic metabolites (VOMs), urine is ideal for non-invasive metabolomics analysis.[1] However, there is still lack of rapid analysis method for VOMs in urine.