RAPID ANALYSIS OF NCI60 PANEL METABOLIC AND LIPID PROFILES WITH AN AUTOMATIC WELL PLATE READER USING LASER ASSISTED REIMS

摘要

In this study, we present an automated, fast and effective way to identify different cell cultures based on their metabolic profile using laser assisted rapid evaporative ionization mass spectrometry (REIMS [1]). The aim of this study was to create an integrated workflow for the automatic analysis of cell line samples from well plates, and the building of a NCI60 cell line database based on the metabolic and lipid fingerprints of the samples.