Electrostatic Spray Ionization (ESTASI) Mass Spectrometry Imaging of Thin-Layer Chromatography

摘要

Recently, we have developed and patented a new ambient ionization method, namely electrostatic spray ionization, to ionize samples in a solution deposited on a plastic plate. In addition to the analysis of samples in solution, ESTASI is also ideally suited for Mass Spectrometry Imaging (MSI) because of its specific property of ambient in-situ ionizing dried samples on a surface or inside a porous matrix without much sample pretreatment.