Determination of Collision Cross-Section and Analysis of Isomeric Vitamin K1 Using Electrospray Ion Mobility Time-of-Flight Mass Spectrometry

摘要

Vitamin K1 isomers separation was demonstrated using IM-MS. Experimental CCS values calculated from drift time and mathematical models showed that it is a reliable analytical method. A single analysis only need few minutes besides the sample preparation procedures, hence, it will provide an effective and efficient analysis method for all-trans-vitamin K1 determination in the domains of food and medicine safety control.