Isotopically Labelled Girard Reagents for Multiplexed Analysis of Oxysterols and Cholestenoic Acids in Plasma and CSF

摘要

The multiplexed analysis of oxysterols provides a powerful tool for lipidomics. The direct comparison of multiple samples increases efficiency by making better use of instrument time, and improves accuracy by negating matrix effects. This method can be used for the rapid diagnosis of inborn errors in cholesterol metabolism.