Routine Targeted Quantitation and Identification of Pesticide Residues using Triple Quadrupole LC-MS/MS and Advanced Scheduling of MRM Transitions

摘要

Recent regulations on food analysis require the screening for pesticides using confirmatory techniques, such as GC-MS(/MS) and LC-MS/MS. With more than 1000 pesticides of more than 100 compound classes there is a demand for powerful and rapid analytical methods, which can detect very low concentrations in a variety of food matrices. Here we present a high-throughput routine LC-MS/MS method that combines screening with identification based on Multiple Reaction Monitoring (MRM) and full scan MS/MS data.