A one-pot synthesis of functionalized 1,3-thiazoles from thioamides and 2-chloro-1,3-dicarbonyl compounds in an ionic liquid

摘要

Ionic liquids (ILs) have gained tremendous attention in the last 15 years. ' They are, among other uses, solvents and are frequently fitted with attributes like "modern", "green", "designable", "non-volatile", "non-coordinating" etc. Many chemical reactions have been attempted and successfully performed in IL media and oftentimes these systems show interesting and peculiar features. Yet, considerable work in IL chemistry is still based on trial-and-error rather than fundamental understanding and rational design.