Mutagenicity of N-Acyloxy-N-alkoxy amides —New Substituent Effects

摘要

N-Acyloxy-N-alkoxyamides (1) are a class of biologically active anomeric amides that mutate Salmonella typhimurium TA100, a point mutation strain, in the Ames test. They are known to react with DNA at N7 of guanine.