Ammonium meso-substituted porphyrins and chlorins, how the reduction of a double bond may affect the physico-chemical properties of PDT agents

摘要

The research for new, alternative strategies to antibiotic treatment of infectious diseases is emerging, due to the spread of antimicrobial resistance, which is recognized as a global health problem by the World Health Organization. Photodynamic Therapy (PDT) could represent a very attractive alternative to antibiotics to fight against pathogens, especially in the case of localized infections [1].