Label-free Shotgun Proteomics Identifies Markers of Inflammation from Fetal Fibroblasts

摘要

1. Col-GFP mice is an effective model to isolate and study dermal fibroblasts directly from scarless and fibrotic fetal skin and wounds. 2. Shotgun proteomics indicate that global protein expression patterns are altered in Col-GFP fibroblasts isolated from E15 and E18 skin. 3. FetA/AHSG may be important for the transition from scarless to fibrotic healing in fetal skin.