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Fast and reliable Quantitation of Z-drug Hypnotics and Benzodiazepines in Serum using UHPLC-QTOF Mass Spectrometry

机译:使用UHPLC-QTOF质谱法在血清中快速可靠地定量Z-药物催眠药和苯并二氮卓类药物

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摘要

The application of LC-QTOF full scan, accurate mass analysis has been shown to deliver accurate quantitative results for the analysis of 13 benzodiazepines and z-drug hypnotics in serum. The adoption of this quantitative high resolution workflow delivers additional analytical flexibility, as it also allows the possibility of retrospective quantitative & qualitative investigations to be undertaken without the requirement for further sample analysis.
机译:LC-QTOF全扫描的应用,准确的质量分析已显示为血清中13个苯二氮卓和Z-药物催眠药的分析提供准确的定量结果。通过这种定量高分辨率工作流程提供了额外的分析灵活性,因为它还允许在不需要进一步样本分析的情况下进行回顾性定量和定性调查的可能性。

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