Monitoring Site Specific Glycosylation of Chimeric Anthrax Antitoxin (CMG2-fc) During Bioengineering Process

摘要

Glycan analysis show that CMG2-Fc was successfully retained in the ER. There is a slight decrease of the site occupancy of asp 297 during the downstream purification process. There was a profound glycosylation profile change after CMG2-Fc was incubated with alpha2mannosidase1.