How homogeneous equilibria between solvated enantiomers can modify the stable and metastable heterogeneous equilibria

摘要

A part of the system [(+)glutamic acid -(-)glutamic acid -HCl - water] has beeninvestigated. It gives evidence that the metastable solubility isotherm of a given enantiomer is located in the biphasic domain of its antipode as long as the solvent does not contain a large excess of chloride anion. This characteristic has been proved by preferential crystallization. Indeed, the stereoselective crystallization of a given enantiomer [e.g.(+)] persists even in a domain where: it should partially dissolve when considering the stable equilibria.