First pass Babesia microti genome annotation

摘要

Babesia microti are hemoprotozoan parasites of the phylum apicomplexa. Entire coding core of the three chromosomes have been assembled for an overall size of 6.4 Mbp. Analysis of orthologues from energy, glycosylphosphatidylinositol biosynthesis and DNA repair pathways revealed mix characteristic of Babesia and Theileria in the B. microti genome.Babesia microti is a tick-transmitted pathogen of rodent and human in United States and Europe. The emergence of B. microti-associated human babesiosis is not only the result of greater awareness of this disease (1).Preliminary PFGE results suggested that B. microti was the smallest known apicom-plexe genome. Furthermore, B. microti is the representative of a group of piroplasms that clustered in a monophyletic assemblage separate from the Babesia sensu stricto and Theileria genera.