The aim of the study was to evaluate intraoperative blood loss in patients who underwent radical prostatectomy or radical cystectomy under general anesthesia (GA) or combined spinal - epidural anesthesia (CSEA). General anesthesia (GA) was conducted by means of endotra-cheal anesthesia with myorelaxation and mechanic ventilation. Combined spinal - epidural anesthesia (CSEA) was conducted using 0.5% solution of bupivacain intraspinal-epidural together with general anesthesia. Radical prostatectomies or radical cystectomies were performed for 62 patients at Vilnius University Institute of Oncology. The number of patients who were operated on under GA was 32, and 30 patients received CSEA. Mean blood loss in CSEA group was significantly lower in comparison with that of GA group (560 + 150 ml vs. 1510 + 260 ml respectively; p < 0.001). Significant reduction of need of transfusion of allogenic blood was observed in CSEA group, in comparison with that of GA group (respectively, 0.9 + 0.3 vs. 2.9 + 0.7 units mean; p<0.001). The complications of surgery or anaesthesia were very seldom, so we found no dependency between them and the mode of anaesthesia.
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