Mathematical and experimental modeling of single droplet drying for 'shrinking' vs. 'ballooning' particles

摘要

Developing pharmaceutical product formulations in a timely manner and ensuring quality is a complex process which requires a systematic, science based approach and combination of information at multiple spatial and temporal scales. Advances in quantitative analysis techniques (e.g. mechanistic models) in combination with modern measurement tools enable engineers to design and scale-up pharmaceutical unit operations and processes with more confidence and reliability.