EFFECTS OF VARIOUS ANTIFUNGAL AGENTS ON REACTIVE OXYGEN SPECIES GENERATION BY CANDIDA ALBICANS

摘要

It is known that Candida albicans can generate reactive oxygen species (ROS), and that some antifungal agents affect the ROS generation. In this study, the effects of seven antifungal agents (terbinafine (allylamine), amorolfine (morfolin), ciclopirox olamine (hydroxypyridone), and four imidazole antimycotics, including miconazole, bifonazole, sulconazole and clotrimazole) on the ROS generation by C albicans were examined on a 96-microtiter plate, using a fluorescence analyser.