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A Versatile Centrifugal Microfluidic Platform for Point-of-Care Diagnostics

机译:用于护理点诊断的多功能离心微流体平台

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We present a novel concept to determine a set of relevant biochemical markers for applications in the field of emergency diagnostics. Our modular setup comprises a disposable polymer disk which hosts microfluidic structures and optical elements for an integrated beam-guidance. The portable analyzer as reusable component features a standard drive to spin the disk, low-cost lasers as light sources and a spectrophoto-meter as flexible detector for different assay formats. The competitive performance of the setup was proven by the rapid and accurate determination of glucose, alcohol, and hemoglobin of human whole blood via absorption measurements. Striking benefits are a full process integration including metering, mixing, and sedimentation of the cellular constituents, and a short time-to-result.
机译:我们提出了一种新颖的概念来确定紧急诊断领域的应用的一组相关的生化标志。我们的模块化设置包括一种一次性聚合物盘,其托管微流体结构和用于集成光束引导的光学元件。便携式分析仪作为可重用组件具有标准驱动器,可使磁盘,低成本激光器作为光源和分光光度计为不同的测定格式。通过吸收测量,通过吸收测量快速准确地确定人类全血的葡萄糖,酒精和血红蛋白的竞争性能。引人注目的益处是一种完整的过程集成,包括细胞成分的计量,混合和沉降,以及较短的时间。

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