CLINICOPATHOLOGICAL ANALYSIS OF THIRTY-TWO PATIENTS WITH AL AMYLOIDOSIS: FOUR-YEARS EXPERIENCE IN A SINGLE INSTITUTION

摘要

Light chain (AL) amyloid causes progressive organ dysfunction that inevitably leads to death Although there are numerous discussions about the best therapy, one thing is very clear: the efficient treatment of AL amyloidosis is essentially determined by the early diagnosis and correct chemical type identification Light chain AL amyloidosis is one-fifth as common as multiple myeloma and its incidence is of approximately 8 cases per million persons a year (1). Therefore the rarity of this disease, together with both the polymorphic clinical manifestations and the complexity of diagnostic investigations account for the difficulty of amyloidosis diagnosis.