AMYLOID DEPOSITION IN THE TONGUE OF PATIENTS WITH FAMILIAL AMYLOIDOTIC POLYNEUROPATHY

摘要

It is well known that dry mouth and dysgeusia are common clinical manifestations in the advanced stage of FAP,, Although labial salivary gland biopsies have been reported as a valuable test to assess amyloid neuropathy, such as FAP and AL amyloid neuropathy, relationship between clinico-pathologic changes remains to be elucidated (1,2). In this study, we evaluated clinico-pathologic changes in the tongue in patients with FAP using histopathological and clinical manifestations.