EFFECT OF ARTIFICIAL GRAVITY WITH EXERCISE LOAD BY USING SHORT-ARM CENTRIFUGE WITH BICYCLE ERGOMETER AS A COUNTERMEASURE AGAINST DISUSED OSTEOPOROSIS

摘要

To evaluate the effectiveness of centrifuge-induced artificial gravity with ergometric exercise to disused osteoporosis, 9 young healthy men were exposed to -6° head-down bed-rest for 14 days. Four out of nine subjects were loaded by intermittent artificial gravity with ergometric workload. The rest of subjects were the control group. The concentrations of urine deoxy-pyridinoline were examined in each subject before and after the bed-rests. The rate of increase of urine deoxy-pyridinoline of the countermeasure group was significantly more suppressed than the control group. This countermeasure can definitely suppress the bone absorption which is caused by 14 days head-down bed-rest; however the effectiveness is still insufficient. More gravitational load or exercise load is still required.