Monte Carlo Cellular Automaton Simulation in Biomedical Science: Heterodimerization of Receptors

摘要

It has become well known that simulation can be used to investigate complex biomedical systems in situations where traditional methodologies are difficult or too costly to employ. Once the model, constructed to represent important aspects of the system under evaluation, has been validated, it may be used to investigate the effects of differences in the system inputs, changes in initial conditions, or its environment, and alterations in the system structure. Many recent advances in technology have greatly enhanced the power and expressiveness of simulation. We give an example where Monte Carlo cellular automaton simulation is employed to study heterodimerization of receptor proteins.