Single Subcutaneous Dose of a Combination Vaccine Containing Bovine Herpes Virus-1 (BHV-1) Provides Protection Against an Intranasal BHV-1 Challenge 72 Hours Later

摘要

Bovine herpesvirus 1 (BHV-1) is associated with several disease syndromes in cattle. The BHV-1 respiratory infections can result in several clinical manifestations that range from inapparent to severe respiratory disease, infectious bovine rhinotracheitis (IBR). Signs include pyrexia, anorexia, conjunctivitis with lacrimal discharge, dyspnea and nasal discharge. BHV-1 respiratory infection in calves and feedlot cattle can lead to the bovine respiratory disease complex (BRDC), with secondary bacterial infections that cause significant economic losses to the livestock industry.