NOVEL FABRICATION METHOD FOR UNIFORM GELATIN MICROSPHERES OF PRECISELY CONTROLLED SIZE AND SIZE DISTRIBUTION

摘要

Uniform gelatin microspheres with precisely controlled size and size distribution were fabricated by combined use of acoustic excitation, carrier stream, particle charging, and water-in-oil emulsion method. A low-temperature bath was used to facilitate gellation of the gelatin drops. Reproducibility and precision of the fabrication process was enhanced by computer-based control of the acoustic excitation and the carrier stream flow.