A cluster of six closely linked STR-markers:Recombination analysis in a 3.6-Mb regionatXql2-13.1

摘要

Three tetranucleotide tandem repeats (DXS10079, DXS10074 and DXS10075) which were unutilised so far were evaluated for forensic use Our investigation was amended to establish a cluster of closely linked markers within a 280-kb region at Xql2 Haplotype stability in 152 meioses was demonstrated in a recombination analysis of 96 three-generation families Three further known markers, DXS7132, HumARA and DXS981 spanning a region of 3 6 M,were also included No recombination events were detected Hence, we conclude that this cluster segregates with stable haplotypes, providing a powerful tool in kinship testing.