Power of exclusion of 18 autossomic STR loci in a Brazilian Middle-West region population sample

摘要

The arm of this work was to analyze the Power of Exclusion (PE) in paternity investigation cases from Federal District of Brazil (Center-West region of Brazil) using a local population sample (n=917) in comparison with Promega Corporation published databank, both for 18 autossomic STR loci. For this purpose, we analyzed 311 cases where the alleged father was excluded The expected and observed values in the exclusion cases were compared by locus and by multiplex system The values of x~2 show a P higher than 0 05 for each locus, except TPOX and D16S539 (0 05>P>0 01), where the observed number of exclusions was higher than the expected ones. The a priori Exclusion Probability to each locus did not differ significantly between the two databases, suggesting that, in the absence of a database population-specific, another databank can be used as reference for estimates of PE and Probability of Paternity, considering similar ancestry in both populations composition, which is the case of Brazil and the United States .