Perturbation Monte-Carlo-based derivative estimation for imaging transport regime tissue optical properties

摘要

In this work we show that for imaging tissue with low scattering background, reconstruction algorithms using derivatives calculated through perturbation Monte-Carlo method worked well whereas diffusion equation based methods failed. An easy way to estimate the Jacobian using analytical expression obtained from perturbation Monte-Carlo method is demonstrated. We have successfully reconstructed both absorption- and scattering inhomogeneities in objects, which fall under transport equation regime. Experimental data gathered from tissue-equivalent phantoms with low-scattering coefficient background and absorption and/or scattering inhomogeneities are reconstructed using the above method.