Palladium Catalyzed Benzylic Substitution of Benzyl Esters

摘要

A palladium complex generated in situ from [Pd(eta~3-C_3H_5)(cod)]BF_4 and DPPF showed high catalytic activity for benzylic alkylation of benzyl methyl carbonate with carbanions of dimethyl malonates.The catalytic reaction is applicable to a wide range of the benzylation of malonates to give the corresponding products in high yields.Palladium-DPEphos complex is superior to the Pd-DPPF catalyst in the benzylic amination of benzylic esters.