Asymmetric Hydrosilylation of Olefins with Rh-Phebox Complexes

摘要

Asymmetric addition of alkoxyhydrosilanes to styrene derivatives was examined with chiral bis(oxazolinyl)phenyl-rhodium complex to give moderate ratios (up to 77:23) of a- and p-adducts and high enantioselectivity up to 95% for the alpha-adduct.The catalytic hydrosilylation system with Rh-Phebox and the hydrosilanes was applied to asymmetric conjugate reduction of alpha,beta-unsaturated carbonyl compounds and subsequent aldol reaction with aldehydes.