Ni-Catalyzed Regioselective Three-Component Coupling Reaction of Terminal Alkynes, Alkyl Halides, and Grignard Reagents

摘要

Recently, transition-metal catalyzed cross-coupling reactions and regioselective alkylation reactions of C-C unsaturated compounds using non-activated alkyl halides have been extensively studied. During the course of our study on these reactions using alkyl halides, we have reported Ni-catalyzed regioselective three-component coupling reaction of dienes, alkyl halides, and aryl metal reagents.