Plasma polymerized ethylenediamine (PPEDA) thin films for cell-adhesive implant coatings

摘要

Plasma polymerized ethylenediamine (PPEDA) thin films (20 nm - 70 nm) were deposited on the powered electrode of the low pressure capacitively coupled 13.56 MHz plasma. The chemical composition of the thin PPEDA films was characterized by FTIR spectroscopy. During storage of the PPEDA films in air, characteristic changes in the FTIR spectrum were observed immediately after deposition and over long-time period of 360 days. Additionally, the adhesion of human osteoblastic cells MG-63 (ATCC) on PPEDA coated samples was investigated. Corundum blasted titanium alloys (Ti6Al4V) were used as specimens. The cell adhesion was characterized by flow cytometry and the cell shape was analysed by scanning electron microscopy. A significant increase of the initial cell adhesion was observed compared with the uncoated reference sample. The enhanced initial cell adhesion is remaining after long-time storage in air.