HOW TO IDENTIFY LATERALLY TRANSFERRED GENES?

摘要

The existence of the phenomenon of Horizontal Gene Transfer (HGT) is one of the important processes by means of which the progress of the evolution is explained. The purpose of this article was to propose a comprehensive and combined mathematical-statistical approach to the identification of HGT events, which is not found in the biological literature. In this article the database consisting of CLCA sequences and 13 whole bacterial genomes was used to test known methods of HGT events' identification. Moreover some new proposals were presented. One of them is the application of new measures, i.e. the angle and the area between the vectors identified with the codon genes. The statistical ranking of all used methods has been developed on the basis of the obtained results.