Coronary Artery Disease in African and Caucasian South Africans

摘要

We retrospectively analysed records of 500 consecutive virgin patients who underwent coronary angiography at Chris Hani Baragwanath Hospital over a 2-year period. Data analysed included demographics, presenting diagnoses, coronary risk factors, coronary artery anatomy, echocardiographic left ventricular ejection fraction (LVEF) and coronary artery disease treatment strategy (medical, PCI or CABG). Of the 206 patients with critical coronary artery disease 85 were black Africans (Africans) and the rest were Caucasians and Asians (non-Africans) South Africans. There were more females and hypertension occurred more frequently amongst the African patients. Serum total (TC) and low-density lipoprotein (LDL-C) cholesterol, and triglyceride levels were significantly lower in the African patients. The prevalence of smoking, diabetes and obesity, and serum high-density lipoprotein (HDL-C) cholesterol were not significantly different between the two patient groups. In addition, presenting diagnoses [acute myocardial infarction (AMI), unstable or chronic stable angina], diseased coronary artery anatomy [left main, left anterior descending (LAD), circumflex (CX) or right coronary7 (RCA) artery] and extend of coronary artery disease (focal or diffuse). LVEF and treatment strategy [medical, percutaneous intervention (PCI) or with coronary artery bypass grafting (CABG) surgery] were not significantly different between the two groups.