Correlation Between GISSI Risk Score Classes and Major Cardiovascular Events in a Population of Patients with Prior Myocardial Infarction

摘要

Patients with known ischemic heart disease have an high cardiovascular risk. In GISSI Prevenzione trial ten classes of risk in patients with a recent or prior myocardial infarction were identified, with progressive increasing risk of death at 4-years follow up. We applied GISSI-Prevenzione risk chart in a real world population of patients with prior myocardial infarction and after two years of follow-up we observed significant differences of events among classes. Coronary artery disease is the primary cause of death in the western world. During the last decades progress has been made in the treatment of patients who survived myocardial infarction. Nevertheless, patients who survive an acute myocardial infarction are at high risk, with life expectancy half that of their peers who have not experienced similar events, and with increased risk for subsequent cardiovascular events. In recent years, it has become clear that in addition to risk factors such as overweight, lack of exercise, smoking, hypertension and hypercholesterolemia, the risk of sudden death increases with severity of systolic dysfunction after myocardial infarction.