The Friedel-Crafts acylation of aromatics is a widely used reaction for the production of many pharmaceutical, agrochemical, and fragrance compound. The conventional Friedel-Crafts method uses Lewis acids such as metal halides and liquid Bronsted acids such as polyphosphoric and sulfuric acid as the catalysts. The reaction is carried out in homogeneous phase and the catalysts must be destroyed to obtain the final products, generating a great amount of corrosive and toxic wastes. In order to eliminate these corrosion and environmental problems, many efforts are being made to find solid acid catalysts, which can successfully carry out acylation reactions for a more environmental-friendly technology. In this study, we employ the recently developed acidic mesoporous aluminosilcates as the solid acid catalyst. MCM-41-S and MCM-48-S were made by using zeolite seeds as the silica source to synthesize strong acidic, hydrothermally stable hexagonal mesoporous aluminosilicates. Using these materials as solid acid catalysts to operate the Friedel-Crafts acylation of aromatics that have high conversion rate and selectivity.
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