Evaluation of the decay in colostrum derived maternal antibodies against Mycoplasma hyopneumoniae in swine

摘要

Mycoplasma hyopneumoniae (M. hyo) is the causative agent of enzootic pneumonia in pigs. A majority of swine herds today are positive for M. hyo. Lately, M. hyo has been identified as one of the major pathogens in the porcine respiratory disease complex (PRDC). M. hyo vaccination produces an efficacious immune response and has been shown to reduce the amount of pneumonic lung lesions in vaccinated and challenged pigs. M. hyo vaccination has also been shown to decrease PRRSV pneumonia in animals that are co-infected with both PRRS and M. hyo. Several studies have shown that vaccination of pigs in the presence of maternal antibodies leads to a decreased immune response to the vaccine. Determining when maternal antibodies decline to a level such that they will not interfere with vaccination is crucial for developing effective vaccination programs.