Decision support of inspired oxygen fraction using a model of oxygen transport

摘要

Setting inspired oxygen fraction (FiO_2) is a complicated balance between ensuring adequate oxygenation and minimizing the risk of lung damage. This paper presents a retrospective test of a model-based decision support system (INVENT) for advising on FiO_2 levels in intensive care patients. Clinically determined FiO_2 levels and the resulting blood oxygenation are compared with INVENT determined FiO_2 levels and model simulated blood oxygenation. The results indicate that INVENT can maintain an acceptable level of oxygenation using similar or more appropriate levels of FiO_2 compared to clinical practice.