Human Serum Albumin-flavonoid Interactions Monitored by Means of Tryptophan Kinetics

摘要

A nonextensive model of decay kinetics has been used to describe fluorescence behavior of trypto-phan in human serum albumin on binding two flavonoids, quercetin and morin. We demonstratethat this approach, alternative to multiexponential representation of usually complex decays oftryptophan, is more adequate and can be beneficial in noninvasive lifetime sensing based onintrinsic fluorescence.