Residential radon and childhood leukemia: a metaanalysis of published studies

摘要

The carcinogenic effect of radon has not been established except for lung cancer. We con-ductedametaanalysisofpublishedepidemiological studies on residential radon and childhood leukemia. Five case-control studies were identified, with a total of 1348 cases and 2057 controls. We used a log-linear regression model to obtain a summary estimate of radon-related risk in each study, based on adjusted odds ratios corresponding to categories for radon concentration. Overall estimate of relative risk at 150 Bq/m~3 was 1.05 (95% CJ: 0.90-1.21) based on random effect model. There is no evidence for an associationbetweenresidentialradon and childhood leukemia.