Analysis of complementarity of protein-protein and protein-DNA interactions using the molecular surface database, eF-site

摘要

Structural genomics project now producing a large number of protein 3D structures, and the structural information will give us a lot of information on the protein molecular functions. On the other hand, it is not an easy task to solve the structure of protein complexes especially when the complexes are transient, even though the formation of such transient complexes has critical roles to express the biological function of proteins. Thus, some techniques to know or predict the structure of transientcomplexes of proteins is now required.