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Identifying genetic network using experimental time series data by Boolean algorithm

机译:通过布尔算法使用实验时间序列数据识别基因网络

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Recently, a variety of experimental techniques for biological field have been developed. These technologies have made it possible to observe the expression of many genes simultaneously and to accumulate a vast amount data. One of the challenging research areas is to extract the genetic networks from these large data. A lot of methods for this problem proposed; quantitative model, statistic model, hybrid model, and Boolean model. However, a lot of these papers analyzed only artificial data and deletion strain data. In this paper, we applied Boolean algorithm for extraction genetic network from experimental time series data. Using binary data that was made from real data, our system was achieved to categorize genes to some equivalence classes and discover genetic interactions.
机译:最近,已经开发了各种用于生物领域的实验技术。这些技术使得可以同时观察许多基因的表达并积累大量数据。其中一个具有挑战性的研究领域是从这些大数据中提取遗传网络。提出了很多关于这个问题的方法;定量模型,统计模型,混合模型和布尔模型。然而,许多这些论文仅分析了人工数据和删除应变数据。本文从实验时间序列数据应用了提取遗传网络的布尔算法。使用由真实数据进行的二进制数据,我们的系统达到了将基因分类为某些等价类并发现遗传交互。

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