Influence of Luminal Pancreatic Juice and Bile on the Secretion of Pancreatic Juice and Bile in Weaned Pigs

摘要

A chronic model was developed to collect pure pancreatic juice and bile in weaned pigs. Effects of pancreatic juice and bile diversion and reintroduction into the duodenum were studied under preprandial and prandial conditions. Diversion of pancreaticjuice increased pancreatic secretion in both of these periods. Diversion of bile increased pancreatic secretion but did not affect bile flow. Diversion of both reduced bile secretion. In conclusion, there is preprandial and prandial feedback control ofpancreatic juice secretion and no bile feedback control in weaned pigs. Bile flow is influenced by pancreatic juice diversion.