New method for improving detection limit of berberine ion selective electrode

摘要

Recently, it was shown that detection limit of ionophore-based ion-selective membrane electrode (ISEs) is determined by a small flux of primary ions from the organic sensing membrane into its aqueous surface layer. Pretsh et al have successfully reduced this small flux by adding ion buffers of EDTA and a high concentration of an interfering ion into the internal solution and achieved a lower detection limit of 5 * 10~(-12)mol/L for Pb~(2+).