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A three dimensional growth model for primary cancer

机译:原发性癌症三维生长模型

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摘要

Maybe the most aggressive phenomena in biology is the growth of cancer cells. In this paper we propose a simple three - dimensional model to simulate the growth of carcinoma, which includes cell proliferation, reciprocal influence among cells, cell division and cell death. Every simulated pattern growth is characterized by its gyration radius, number of cells on tumor periphery and fractal dimension. We use the DLA model and computer simulation to characterized the growth phenomenal. The Application Of DLA(Diffusion-Limited Aggregation) model to generate fractals structure is shown in this work. The similarity between this computational model and some abnormal cell growing, are shown as well. We use a Hash function to the DLA in three-dimension problem, the possibility of developing studies in higher dimensions without affecting the required time by the algorithm is show. Also, a comparison between the simulated patterns and explants of primary tumors is done.
机译:也许生物学中最具侵略性的现象是癌细胞的生长。在本文中,我们提出了一种简单的三维模型来模拟癌的生长,包括细胞增殖,细胞,细胞分裂和细胞死亡之间的相互影响。每个模拟模式的增长的特征在于它的血管半径,肿瘤周边和分形尺寸上的细胞数。我们使用DLA模型和计算机模拟来表征增长现象。在这项工作中示出了DLA(扩散限制聚集)模型产生分形结构的应用。也显示了该计算模型与一些异常细胞生长之间的相似性。我们在三维问题中使用哈希函数在DLA中,显示在不影响算法的情况下,在不影响所需时间的情况下在更高的尺寸下开发研究的可能性。而且,完成了原发性肿瘤的模拟模式和外植体之间的比较。

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