Cathepsin D produces the potent antimicrobial peptide parasin I from histone H2A in scaleless fish skin

摘要

Antimicrobial peptides have been known to act as the first line of mucoal host defense by exerting broad-spectrum microbicidal activity against invading pathogenic microbes.Recently,a potent 19-residue linear antimicrobial peptide,named parasin I,was isolated from the skin mucus of wounded catfish,Parasilurus asotus.