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UNDERSTANDING TOXOPLASMOSIS

机译:了解弓形虫病

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Toxoplasma gondii is a widespread zoonotic protozoan. Its host range includes a variety of birds and most mammals. Felids are the definitive hosts for this organism, and are the only animals that pass oocysts in their feces. Other hosts develop infective tissue cysts. Most feline infections occur postnatally through ingestion of infective tissue cysts, or rarely oocysts, although congenital infections can occur. Feline infections are typically asymptomatic. Among symptomatic infections, congenitallyinfected kittens are the most severely affected (1). For humans, T. gondii infection can cause severe neurologic or ocular disease in the fetus if acquired during pregnancy. In general, humans usually acquire their infection (a) from ingestion of oocyst-contaminated soil or water; (b) from tissue cysts in undercooked meat; or (c) congenitally (1). Most people infected after birth are asymptomatic, however a minority may develop fever, malaise, and lymphadenopathy. In rare cases, postnatally infected humans may develop ocular complications (e.g., retinochoroiditis). Toxoplasmic encephalitis, pulmonitis, or other systemic disease may be seen in patients with immunosuppressive disorders.
机译:弓形虫是一个普遍的人群原生动物。其主机范围包括各种鸟类和大多数哺乳动物。 Felids是这种生物的最终宿主,是唯一通过粪便中卵囊的动物。其他宿主显影感染组织囊肿。尽管可以发生先天性感染,但大多数猫科动物感染通过摄入感染组织囊肿或很少卵囊发生。猫的感染通常是无症状的。在症状性感染中,共生的小猫是受影响最严重的(1)。对于人类而言,如果在怀孕期间获得,T.Gondii感染可能会导致胎儿的严重神经系统或眼部疾病。一般来说,人类通常从摄取卵囊污染的土壤或水中获得它们的感染; (b)从未煮熟的肉中的组织囊肿;或(c)共同(1)。大多数人在出生后感染无症状,但少数群体可能会发烧,不适和淋巴结病。在极少数情况下,出现后感染的人类可能会产生眼部并发症(例如,视网膜体炎)。免疫抑制疾病患者可能会看到弓形虫脑炎,肺炎或其他全身疾病。

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