Evaluation of ganciclovir-loaded albumin nanoparticles for the treatment of cytomegalovirus infections

摘要

Human cytomegalovirus (HCMV) infections are a major cause of morbidity and mortality in immunocompromised patients. Moreover, disseminaed HCMV infections are often associated with retinitis~1. Therefore, the incidence of retinal infections reached levels as high as 60 percent in AIDS patients~2.